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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Pii nitrogen regulatory proteins ： ウィキペディア英語版 Pii nitrogen regulatory proteins The Nitrogen regulatory protein P-II family contains a series of homologous prokaryotic signalling proteins which are involved in the regulation of nitrogen metabolism. The proteins are post translationally modified via addition of a uridylyl group by the enzyme Uridylyltransferase. The presence or absence of this group modulates the behaviour of the protein. In turn, uridylation is controlled by cellular levels of alpha=ketoglutarate and ATP. PII proteins exist in trimers in vivo and bind ATP in a cleft between the subunits. There are two flexible loops call the B-loop and T-loop which are involved in regulation of the protein. The T-loop contains a conserved tyrosine which is the site of uridyl attachment. Following nitrogen starvation, increased intra-cellular concentrations of ammonia cause the de-uridylylation of GlnK. This then binds directly to the ammonia channel AmtB to block ammonia conduction. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Pii nitrogen regulatory proteins」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.